Tuesday, April 20, 2010

In Our Coloradoan Newspaper today....If we all did this safe alternative herbicides would become the norm...

Boulder residents protest spraying dandelions
BOULDER, Colo. (AP) — Residents of a south-Boulder neighborhood say they'll lie down in front of chemical sprayers to prevent the use of an herbicide to kill dandelions.
The protest is planned Friday at the Shanahan Ridge 7 condos. Condo owner Roz Lynn Dorf says there are organic ways to get rid of the dandelions. The 61-year-old Dorf says about half the 160 residents have signed a petition asking the management company to not use chemical herbicides on the property because of concerns about the effects.
The condo association's board of directors says in a written statement that it went with a conventional treatment after alternative treatments proved too costly. The board says it will keep looking for chemical-free alternatives

Monday, March 8, 2010

Sadly...Panel kills bill barring some beauty products.

Panel kills bill barring some beauty products
By Jessica Fender
The Denver Post
Posted: 03/02/2010 01:00:00 AM MST
Updated: 03/02/2010 01:59:27 PM MST

Some products the bill targeted are, from left: T/Gel shampoo; Johnston's Bedtime Bath; Just for Me Conditioning Creme; Soft-soap; L'Oreal hair color, and Old Spice deodorant. (John Prieto, The Denver Post)
Fifteen harmful chemicals, including formaldehyde and arsenic, will remain in beauty products in the state after a legislative panel Monday killed a proposal that would have prohibited the sale of toiletries and cosmetics that contain them.

Bill backers argued that while safe in the small doses at which the compounds appear in hand creams and shampoos, those traces accumulate over time and over multiple products.

The prohibition — pitched as a way to fight cancer and reproductive disorders — would have been the toughest of any state regulating cosmetics ingredients.

But several committee members protested that the science linking the products to cancer just wasn't there and that many of the problem

Extras
Keep up with the latest political events and opinion at The Spot politics blog.
Full political news coverage at denverpost.com/politics.
chemicals appear elsewhere in the environment — sometimes occurring naturally.

"Nobody's been able to draw a causal connection between the use of cosmetics and cancer," said committee member Rep. Mark Waller, a Colorado Springs Republican who voted against House Bill 1248.

The legislation would have regulated the Colorado sale of beauty and personal-care products based on lists of chemicals that are banned in Canada and the European Union.

Companies found selling products containing lead, benzine, chloroform or the other substances would have been fined up to $100,000 under the bill, which failed 7-4 on a bipartisan vote.

University of Colorado-Boulder professor David Norris studies how chemicals in the environment affect organisms. He said that while personal products aren't the only source of dangerous chemicals, they're a good place to start.

"Nobody's exactly at fault," Norris said. "It's the aggregate of all these things."

Several opponents argued that chemists can find tiny amounts of the 15 chemicals in any number of products if they look hard enough, and the rules would have opened up companies to frivolous lawsuits.

California requires companies to publicly disclose products that contain chemicals that may cause cancer or reproductive problems, according to the policy research group the National Conference on State Legislatures.

Missouri and New York are considering similar rules and a handful of other states bar mercury from certain products, NSCL data show. None bans outright the sale of goods.

Colorado state Rep. Dianne Primavera, D-Broomfield, said there's enough evidence that some cosmetic ingredients can cause cancer to take preventive measures before definitive studies are done.

"You shouldn't have to be a chemist to shop for shampoo," Primavera said.

Jessica Fender: 303-954-1244 or jfender@denverpost.com









Read more: http://www.denverpost.com/politics/ci_14495236#ixzz0hbVWd0XG



Read more: http://www.denverpost.com/politics/ci_14495236#ixzz0hbVWgHwC

Saturday, February 27, 2010

Derived from flowers, but not benign:

Pyrethroids raise new concerns

Chemicals derived from flowers may sound harmless, but new research raises concerns about compounds synthesized from chrysanthemums that are used in virtually every household pesticide. For at least a decade, pyrethroids have been the insecticide of choice for consumers, replacing organophosphate pesticides, which are far more toxic to people and wildlife. But evidence is mounting that the switch to pyrethroids has brought its own set of new ecological and human health concerns.

By Ferris Jabr

Environmental Health News

February 26, 2010

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kaunokainen/flickr.
Pyrethroids are found in more than 3,500 products used inside homes and on crops, yards, and gardens. Although human health risks are unknown, animal studies have found evidence of damage to neurological, immune and reproductive systems.

Chemicals derived from flowers may sound harmless, but new research raises concerns about compounds synthesized from chrysanthemums that are used in virtually every household pesticide.

For at least a decade, pyrethroids have been the insecticide of choice for consumers, replacing organophosphate pesticides, which are far more toxic to people and wildlife. But evidence is mounting that the switch to pyrethroids has brought its own set of new ecological and human health risks.

About 70 percent of people in the United States have been exposed to pyrethroids, with children facing the highest exposure, according to a study published this month. Although the human health threats are unknown, animal studies have found evidence of damage to neurological, immune and reproductive systems.

In addition, pyrethroids are flowing off yards and gardens, contaminating some streams and rivers at concentrations that can kill small creatures vital to the survival of fish and other aquatic life. Both California and the U.S. Environmental Protection Agency are reevaluating the chemicals because of safety concerns.

“Pyrethroids are obviously a safer alternative to organophosphates, but just because they are safer doesn’t mean they are safe,” said Dana Boyd Barr, a research professor of environmental health at Emory University’s Rollins School of Public Health in Atlanta, Georgia. Barr authored a study that for the first time has measured pyrethroid exposure in the U.S. population.

Pyrethroids are found in more than 3,500 products used inside homes and on crops, yards, and gardens - including lice shampoos, indoor foggers, flea sprays for pets and pesticides to fight ants, wasps, mosquitoes, aphids and spiders. Consumers can identify pyrethroids in products by checking labels for compounds that end in “thrin,” such as bifenthrin, permethrin and cypermethrin.

The compounds are synthetic versions of naturally occurring insecticides called pyrethrins harvested from chrysanthemum flowers. Chemists alter the structure of the pyrethrin molecule to make it more stable in sunlight and to increase its toxicity. The chemicals kill insects by interfering with basic nerve cell functioning. Insects and other invertebrates are highly susceptible to them, while birds and mammals are better able to counteract their effects.

In the new study, 5,046 urine samples collected from U.S. adults and children between 1999 and 2002 were tested for five metabolites of pyrethroid insecticides. Metabolites are the result of the body breaking down a chemical.

Traces of at least one pyrethroid metabolite were found in 75 percent of the people tested in 2001-2002, up from 66 percent in 1999-2000. Children’s concentrations were more than 50 percent higher than the amounts found in adolescents and adults, according to the study by Barr and colleagues published online in Environmental Health Perspectives on Feb. 3.

Children are more highly exposed to pyrethroids because “they spend a lot more time on the floor and have much more hand to mouth activity,” Barr said. “Pyrethroids tend to accumulate in dust or on surface areas in homes because they don’t evaporate easily into the air.” A 2008 study found pyrethroids and their metabolites in vacuum cleaner dust collected from homes and daycare centers in North Carolina and Ohio.

In addition to inhaling or absorbing pyrethroids that linger in households, people ingest traces of pyrethroids in their food, since the chemicals are used on some vegetable, fruit and grain crops.

A 2006 EPA review found that the risk of exposure through diet was at or below the agency’s level of concern for most people. But the study also found that infants and toddlers are highly exposed in some foods, especially bananas, pineapple and dried-oat baby food.

“Pyrethroids are obviously a safer alternative to organophosphates, but just because they are safer doesn’t mean they are safe.” -Dana Boyd Barr, Emory University Rollins School of Public Health“Now that we know people are exposed to pyrethroids widely, we need to determine what the exact health effects are,” said Barr.

So far, there is little scientific data evaluating the potential threat to human health.

Studies with lab animals have linked pyrethroid exposure to damage of the thyroid, liver and nervous system, as well as impairment of behavioral development, changes in the immune system and disruption of reproductive hormones, according to the 2006 EPA review. These animal studies are relevant to human health because pyrethroids act on functions of the nervous system common to all animals, according to the EPA.

Some pyrethroids imitate the hormone estrogen and can increase levels of estrogen in breast cancer cells, and some are suspected carcinogens. Other data suggest that people using the chemicals are at risk of aggravated allergies or asthma, although the EPA concluded last year that there is no clear link.

Pesticide manufacturers say that pyrethroids are safe and that they are vital to agriculture and to combating mosquitoes that carry West Nile Virus and other diseases.

“Pyrethroids are an extremely important class of insecticidal compounds with major public health and agricultural uses,” Rex Runyon, a vice president at CropLife America, a trade group that represents pesticide companies, said in an email. Runyon added that pyrethroids “do not pose unreasonable effects to human health or the environment” when used according to the directions on the label.


Donald Weston/UC Berkeley
Toxic concentrations of pyrethroids from urban runoff were found in the American River in Folsom, Calif.

Although little data exist about human health concerns, evidence is growing that pyrethroids might be harming aquatic ecosystems. Studies of streams and rivers in California, Texas and Illinois suggest that the pesticides might be wiping out small organisms that live in the waterways and form the base of the food chain.

In addition, some studies have shown that pyrethroids can have effects on the growth and reproduction of freshwater fish.

A 2009 study found the pesticides in urban stream sediments in central Texas, where they are widely used to control fire ant and grub worm infestations. The concentrations are lethal to a small, shrimp-like crustacean called Hyalella azteca - a species commonly used in laboratories to investigate the effects of pesticides on invertebrates necessary for healthy rivers.

“All of our sampling sites were very close to neighborhoods with manicured lawns,” said Jason Belden, an Oklahoma State University zoologist and author of the study published in the journal Environmental Pollution. “Some people are not following the best management practices. They’re not being careful enough with pesticides. We all need to make an effort to only use pesticides when we need them.”

Pyrethroids are showing up not only in sediments, but also in the currents of California rivers, at levels toxic to insects and aquatic invertebrates that fish and other animals feed on.

Biologist Donald Weston of the University of California, Berkeley, looked for the insecticides in urban runoff, sewage treatment plant effluent, and agricultural drains in California’s Sacramento-San Joaquin River Delta. In the laboratory, Weston tested the toxicity of these samples on the shrimp-like Hyalella azteca.

“Virtually every drop of runoff from urban communities was toxic to Hyalella because of pyrethroids,” Weston said.

For the first time ever, Weston and his team documented pyrethroids in the outflow of sewage treatment plants, which was surprising.

“About half of the waste water treatment plants we sampled were toxic,” Weston said. “Most people wouldn’t have expected pyrethroids to get through the system. People figured they would be captured by the slush at the bottom - and probably many of them are - but there is enough getting through the system to make the runoff toxic.”

Agricultural drains, on the other hand, were only an occasional source of pyrethroids, according to the study, published this month in Environmental Science and Technology.

“When you say ‘pesticides,’ I think the average person on the street tends to think of agriculture,” Weston said. “They don’t tend to think of the suburban homes, whereas it turns out the suburban home was a constant source of pyrethroid toxicity.”

“Some people are not following the best management practices. They’re not being careful enough with pesticides. We all need to make an effort to only use pesticides when we need them.” -Jason Belden, Oklahoma State University The study demonstrated toxicity in two urban creeks and in a 30-kilometer stretch of the American River, considered one of the cleanest rivers in the Delta region.

“The water is totally clear - as clear as the water that comes out of your bathroom faucet,” said Weston. “But the last 30 or 40 miles of the river, once you start getting into Sacramento, are very heavily urbanized. All these communities are dumping their storm water into the American River and it’s enough to cause toxicity.”

Weston said that finding the chemical in the water itself - not just in the sediments - is cause for concern.

“Pyrethroids are very sticky and they don’t like to be dissolved in the water, so most of them are in the sediments,” Weston said. “But it takes so little in the water to be toxic - only two parts per trillion. The state of California now knows not only do they have to worry about the sediment particles, they have to worry about the water as well. And the water travels much farther downstream.”

The levels of toxicity Weston recorded were more than enough to kill a whole host of insects and other invertebrates necessary for healthy river ecology. The researchers have not documented that creatures in the streams have died. But if the water and sediment samples are toxic to the crustacean in the lab, it is a sign they will be toxic to similar creatures in the waterways.

“I think it’s a good idea to minimize pesticide exposure of any sort, not only because of what we know, but because of what we don’t know.” -Donald Weston, University of California-Berkeley “Bottom dwelling invertebrates and things like stoneflies and mayflies are basically the bottom of the food chain. The concern is whether these insecticides are cutting out this lower rung that the fish depend upon,” Weston said. “This would have not only ecological consequences, but recreational and commercial consequences.” Weston added that the levels in the streams "are not enough to be toxic to a fish, but the fish obviously have to eat."

In response to the toxicity concerns, California's Department of Pesticide Regulation began reevaluating regulation of pyrethroids in 2006. The state has requested additional data from manufacturers on the safety of pyrethroids and is analyzing at least 700 products used in households and on farms.

When mounting the review, Mary-Ann Warmerdam, director of the state’s pesticide agency, told the Los Angeles Times that the state’s evaluation “is a shot across the bow to the manufacturers that we found a reason for concern and you need to provide us with data to either eliminate the concern, reformulate your products or consider taking them off the market.”

California, Weston said, doesn’t want to return to using organophosphates such as chlorpyrifos, which was banned from household use because of human health concerns, “but they want to control the use of pyrethroids to minimize the environmental effects we document.”

“The state of California has the power to ban a product based on the outcome of the reevaluation,” Weston said, “but I don’t think anyone is expecting that to occur. More likely there will be further regulations pertaining to the use of pyrethroids.”

Also, the EPA this year is reevaluating pyrethroids as part of its 2010 pesticide review. The EPA systematically evaluates all registered pesticides every 15 years. Potential outcomes include banning pyrethroids in certain areas, tightening policies or no change to the regulations. However, the EPA process will take another six to eight years.




Mr.Mac2009/flickr
Consumers have alternatives to synthetic pyrethroids -- such as planting chrysanthemums, which contain natural pyrethroids.
Also, an insecticide called fipronil has partially replaced pyrethroids for controlling termite and ant infestations in some areas. Like pyrethroids, fipronil is far less toxic to birds and mammals than other insecticides, but can still kill small aquatic life.In the meantime, there are some alternatives for consumers. Barr suggests products extracted from vegetables and herbs or planting chrysanthemums around the garden. Natural pyrethrins found in chrysanthemum plants do not persist in the environment like the synthetic versions do. Another option for killing some pests is boric acid.

Weston says switching to another chemical is not the solution: he believes people need to fundamentally change how they use pesticides. Many people apply so much to their yards and gardens that the chemicals flow into waterways.

“I think it’s a good idea to minimize pesticide exposure of any sort, not only because of what we know, but because of what we don’t know,” Weston said. “I don’t think a lot of those products are needed. The less you can use them, the better.”

Wednesday, February 10, 2010

Scented Products...Intoxicating and Toxic

Scented Products

Intoxicating and toxic

Walking into my teenage son's room the other day, I nearly gagged. No, it wasn't the smell of unwashed clothes or half-eaten food that got me. It was the opposite problem—air freshener. His own personal can.

I know what you're thinking. He's up to something. Well, maybe...but if he is, this isn't the sign.

("It's good you put that in," he says on reading the preceding paragraph. "Otherwise, people might think you were gullible.")

Like many young people, my son has been conditioned to expect everything to have a good smell—not the genuine good smell of things themselves nor of fresh air wafting in from an open window, but an aggressively pleasant, artificial smell.

(He nods in agreement.)

It's a mark of the times. From fabric softener to garbage bags, and moisturizer to lip gloss, today's household and personal care products are perfumed. Cleanser companies encourage us to choose their products based on scent rather than cleaning properties. Personal care items are advertised as fashion statements. The deodorant made by Secret is promoted, literally, as a form of self-expression.

(I lose him here, but not before getting his consent to publish the above.)

To me, it's absurd, but I'd say "to each his own" if it were just a question of fashion. Unfortunately, it's also a matter of health. An individual fragrance may be made with dozens if not hundreds of synthetic chemicals and need not be cleared for safety before going to market. As a result, dangerous substances may be—and are—routinely added to the cosmetics, cleansers and laundry products that end up in our homes.

Not only doesn't government require safety testing. It doesn't require that the ingredients in fragrances be identified on product labels. The ingredients are protected as trade secrets. And our right to know what chemicals we're exposed to? Trumped, for now, by the fragrance industry.

However, we are not totally in the dark, thanks to independent testing done by academics and public interest groups such as NRDC. What these tests show is not reassuring.

A 2007 study of air fresheners by NRDC found phthalates (pronounced tha-lates) in 12 of 14 brand-name products tested, including some marketed as "all-natural" or "unscented." Phthalates are endocrine disruptors that can cause hormonal abnormalities, birth defects and reproductive problems. None of the air fresheners tested listed phthalates on its label.

Similar results were found in a 2002 study of cosmetics by a coalition of environmental and public health organizations. In this case, phthalates were identified in 52 of 72 products tested. While a follow-up study conducted in 2008 found some reduction in their use, many personal care products for men and women still carry these dangerous chemicals.

Other hazardous chemicals in fragrances include volatile organic compounds, some of which are carcinogenic and cause neurotoxic and respiratory effects. Another class of chemicals of concern is synthetic musks, which, according to preliminary research, may be endocrine disruptors, like phthalates.

For reasons that are not yet well understood, fragrances also seem to trigger allergic-like reactions in certain people. The phenomenon—called multiple chemical sensitivity (MCS) or sometimes sick building syndrome—can be terribly disruptive to sufferers' lives. People with MCS may experience headaches, nausea, confusion, abdominal pain and a host of other symptoms when exposed to common chemicals at levels others find tolerable.

So should you buck the trend and eliminate or cut back your use of scented products? Yes, it's the safe thing to do. These chemicals may have long-term effects not just on you and your family, but if you are of reproductive age, children to come.

How should you go about it?

Do not rely on product claims of being "unscented" or "fragrance-free." A product labeled as such may still be made with fragrances. It's just that the purpose of the fragrance is to mask the natural odor of other ingredients, instead of giving off a detectable scent. From a health and safety standpoint, it's all the same.

Nor should you rely on the words "natural," "organic" or "hypoallergenic." They do not guarantee the absence of fragrance.

Instead, avoid air fresheners, use fewer cosmetics and little or no perfume, consult online resources to find safe products, and try truly natural cleaning agents: water, white vinegar and baking soda. See the sidebar for more specific tips, including product look-up information.

As to my own efforts to protect my son—I've thrown out his air freshener and forbade him to get more. Our next battlefront: deodorant.

—Sheryl Eisenberg






Related TGLs


Pollution in People
Keeping chemicals out of your body
Clean Enough
If the bottle says "danger" or "poison," switch!
The Cost of Shampoo
Is animal testing on cosmetics necessary?


HOW TO AVOID TOXIC FRAGRANCES
•Avoid air fresheners. Open the windows instead.


•Use water, white vinegar and baking soda for routine cleaning jobs. If soap is needed, try castile soap.


•Look up fragrance-free products and homemade alternatives in the Guide to Less Toxic Products.


•Check Skin Deep, the Environmental Working Group's cosmetic safety database, to see if your favorite personal care products are safe and to find safer alternatives.


•Make sure the words "fragrance" or "parfum" do not appear in the ingredient list of cosmetics.


•Use fewer cosmetics and reduce or eliminate your use of perfume.
NATURAL AIR FRESHENERS


2)A simmering pot of spices, such as cinnamon and cloves, in water. Turn the burner off after the scent spreads through the rooms so as not to waste energy.

3)Baking soda. Put an open box in small, enclosed spaces such as the refrigerator to deodorize the air.

Resources


NRDC
Clearing the Air: Hidden Hazards of Air Fresheners

Campaign for Safe Cosmetics
Not Too Pretty: Phthalates, Beauty Products & the FDA and A Little Prettier

Rodale
VOCs and Laundry

Environmental Working Group
Skin Deep: Cosmetic Safety Database

Environmental Health Assoc. of Nova Scotia
Guide to Less Toxic Products

Thursday, February 4, 2010

Professor Urges Us toTake People with Chemical Sensibility into Account‏

Yesterday (Feb 2, 2010), in an independent student newspaper from the University of New Hampshire, a professor of chemical engineering appealed to the community to take “Canaries” into account regarding the use of chemicals and especially scents. He spoke of those persons who suffer from Chemical Sensitivity and who have to be seen – like those former canaries in mines – as indicators for toxic chemicals.

Some American and Canadian Universities have a “Scent Free Policy” which means that the use of perfumes and products containing scents is prohibited within these Universities. All visitors have to meet this policy. It allows students with allergy and chemical sensitivity to work and study.

Professor Ihab Farag, Chemical Engineering Department:

Many of us are familiar with canaries, the beautiful, colorful birds that tend to sing most of the time. Canaries also saved many human lives in coalmines. This is because canaries are much more sensitive to toxic gases than humans. Miners would take canaries with them in the coalmine. If the canary stopped singing and fell (or died), the miners knew to leave the coal mine quickly to safety.

There are individuals who have developed a very strong sensitivity to many common chemicals. These people can be very negatively affected and irritated by fumes, chemical cleaners, disinfectants, cigarette/cigar smoke, engine exhaust, solvents, etc. These people are often called “Human Canaries” of the modern world, because of the chemical sensitivity similarity to that of Canaries. Human Canaries of the 21st century tend to be very strongly irritated by everyday chemicals like perfumes, hair products, shampoos, shower gels, after shave lotions, antiperspirants, deodorants, hand sanitizers, chap sticks, finger nail polish, etc. Human canaries look the same as other people, and when you see one you probably will not recognize he or she is a human canary until an offensive toxic chemical triggers his or her sensitivity.

Please be considerate to human canaries and help them to enjoy life to the fullest. One way you can help the human canary and at the same time lower your exposure to undesirable chemicals, is to go fragrance-free: avoiding perfumes, and fragranced personal care products.



Author: Silvia K. Müller, CSN – Chemical Sensitivity Network, February 2, 2009

Reference:

Chemical consideration to the Human Canaries, Ihab Farag, Professor, Chemical Engineering Department, Letter to the editor 02-02-10, The New Hampshire, Independent Student Newspaper at the University of New Hampshire since 1911, Februar 2, 2010

Wednesday, February 3, 2010

Chemical Sensitivities and Perfume

Chemical Sensitivities and Perfume

Fragrances are now used in almost every cleaning, laundry, and personal-care product on the market. Since people have been using perfumes for hundreds of years. It’s reasonable to wonder why the problem of using scents has surfaced only recently. Until the 20th century, perfumes were made from natural ingredients derived directly from plants and animals, and as fragrances became cheaper and more widespread, they also became more synthetic. The National Academy of Sciences reports that 95% of the chemicals used in fragrances today are synthetic compounds derived from petroleum, including known toxins capable of causing cancer, birth defects, central nervous system disorders and allergic reactions. We have been brainwashed by the industry to feel we must cover up our natural scents with toxic chemicals. Many of the same chemicals in perfumes are the same chemicals that are in cigarette smoke.



You would think the government would protect people by attempting to regulate the industries that are causing harm; however, the cosmetic industry is self regulated and isn’t required to give formulations, test results, safety data or consumer complaints to the FDA. When you use perfume or cologne, remember you are using powerful chemicals regulated solely by the industry that sells them. Just because they don’t affect you now doesn’t mean they won’t affect someone in line next to you (giving them a migraine or sinus problems), or that you will always be immune to their effects. These chemicals go directly into the blood stream when applied to our skin, and are also absorbed into the skin from our clothing. We also inhale these chemical fumes that go straight to our brains where they can do major harm, and many of these chemical fumes have a “narcotic” effect.
(“Smelling Good But Feeling Bad, Synthetic Perfumes, Colognes and Scents Are Turning Up Noses,” Green Living Your Health, and “The Health Risks of Perfume and Other Scented Products,” emagazine.com - March 2002} Author's comment: These effects from scents can surface days after the exposure, and many people do not connect the strong perfume/cologne smell on the lady or gentleman next to them at the opera to their headache or upset stomach days later.




--------------------------------------------------------------------------------



One of the big toxic offenders is perfume and other scented products. Did you know that many of the ingredients in your perfume are the exact same ingredients found in gasoline???!! The scary thing is that the perfume industry is not regulated at all, and they can put any number of chemicals in fragrance without revealing what those chemicals are, and how they affect humans. We humans are all participating in a giant “lab” experiment against our knowledge and against our will, and it is making some of us very sick.


{“Multiple Chemical Sensitivity - Environmental Illness,” www.ourlittleplace.com place.com - April 2002}

Wednesday, January 27, 2010

Household Chemicals Linked to Reduced Fertility

From the LA Times:

Household chemicals linked to reduced fertility Flame-retardant chemicals found in many household consumer products mayreduce fertility in women, researchers reported today. Their study joinsseveral other papers published in the last two years suggesting that thechemicals, polybrominated diphenyl ethers, or PBDEs, affect human health. PBDEs have been used as flame retardants for four decades and are found infoam furniture, electronics, fabrics, carpets and plastics. The chemicalsare being phased out nationwide, and certain PBDEs have been banned for usein California. But they are still found in products made before 2004.Californians may have higher exposures compared with residents of otherstates because of the state's strict flammability laws, according to thestudy authors, from UC Berkeley. Most of the previous research on the chemicals has been in animals. But a2008 study linked the chemicals to disrupted thyroid levels in men, and astudy published this month tied PBDE exposure in pregnancy toneurodevelopmental delays in young children. "These are association studies. You can't show cause and effect," said Dr.Hugh Taylor, an expert on endocrine-disrupting chemicals at Yale Universitywho was not involved in the new study. "But we have cause-and-effectstudies in animals, and we have association studies in humans. I think thatis fairly convincing." In the study, published today in the journal Environmental HealthPerspectives, researchers measured PBDE levels in blood samples from 223pregnant women. The women, who were primarily Mexican immigrants living inan agricultural community, were asked to recall how long they had beentrying to become pregnant, which was defined as being sexually activewithout the use of birth control. Women with the highest concentrations of the chemicals experienced a longerdelay before pregnancy. Each 10-fold increase in blood concentration ofPBDEs was linked to a 30% decrease in the likelihood of becoming pregnanteach month. "It's a pretty strong effect," said Kim Harley, the lead author of thestudy and associate director of the Center for Children's EnvironmentalHealth Research at UC Berkeley's School of Public Health. "They can allbecome pregnant, but they all had very different amounts of time it tookthem to become pregnant." Previous studies suggest that 97% of Americans have detectable levels ofthe substances in their blood. PBDEs are also found in some foods,particularly dairy products and higher-fat meat and fish, but householdproducts are considered a major source of exposure. "PBDEs have the ability to just leach out of these products into ourenvironment," Harley said. "We're thinking the routes are probablyingestion or hand to mouth. But it seems that the larger route of exposureis house dust." How the chemicals might impair fertility is unclear, she said. "One of the strongest associations of PBDEs is with thyroid hormone,"Harley said. "Thyroid hormone does seem to play an important role infertility. Either too low or too high levels can impair fertility. PBDEsalso seem to mimic estrogen. It could be through a hormonal mechanism. Butwe need more research on that." Fertility may be one of the first biological processes affected by chemicalexposures, said Taylor, director of reproductive endocrinology andinfertility at Yale. "Fertility is easy to perturb," he said. "Miscarriage is another thing thatmay be related to environmental exposures. We also have to ask: What arethe effects on the next generation? We know these endocrine-disruptingchemicals can affect the next generation's fertility. Is it due to themother's exposure?" Last month, the Environmental Protection Agency and the two largestmanufacturers of one type of PBDE agreed to phase out the chemical.However, the substances will be in the environment a long time, Harleysaid. And understanding their effects is important. "The thing is, they are used in these durable goods that we have in homes,"she said. "Couches, chairs, TVs, carpet padding. These are things that willstay in our house for years to come."

shari.roan@latimes.com Copyright © 2010, The Los Angeles Times